Resource scheduling of workflow multi-instance migration based on the shuffled leapfrog algorithm

Purpose: When the workflow changed, resource scheduling optimization in the process of the current running instance migration has become a hot issue in current workflow flexible research; purpose of the article is to investigate the resource scheduling problem of workflow multi-instance migration. Design/methodology/approach: The time and cost relationships between activities and resources in workflow instance migration process are analyzed and a resource scheduling optimization model in the process of workflow instance migration is set up; Research is performed on resource scheduling optimization in workflow multi-instance migration, leapfrog algorithm is adopted to obtain the optimal resource scheduling scheme. An example is given to verify the validity of the model and the algorithm. Findings: Under the constraints of resource cost and quantity, an optimal resource scheduling scheme for workflow migration is found, ensuring a minimal running time and optimal cost. Originality/value: A mathematical model for resource scheduling of workflow multi-instance migration is built and the shuffled leapfrog algorithm is designed to solve the model.Peer Reviewe

On-Line Monitoring and Fault Diagnosis of Box Transformer Substation Based on VPRS-RBFNN

Box transformer substation (BTS) is an important power distribution environment. To ensure the safe and stable operation of the power distribution system, it is critical to monitor the BTS operation and diagnose its faults in a reliable manner. In the Internet of Things (IoT) environment, this paper aims to develop a real-time and accurate online strategy for BTS monitoring and fault diagnosis. The framework of our strategy was constructed based on the IoT technique, including a sensing layer, a network layer and an application layer. On this basis, a BTS fault diagnosis method was established with variable precision rough set (VPRS) as the pre-network and the radial basis function neural network (RBFNN) as the back-fed network. The VPRS and the RBFNN were selected, because the BTS faults have many characteristic parameters, with complex nonlinear relationship with fault modes. Finally, a prototype of our strategy was developed and applied to the fault diagnosis of an actual BTS. The results fully demonstrate the effectiveness and feasibility of our strategy

TLR3 Regulated Poly I:C-Induced Neutrophil Extracellular Traps and Acute Lung Injury Partly Through p38 MAP Kinase

Acute lung injury (ALI) is the leading cause of morbidity and mortality in critically ill patients. Neutrophil extracellular traps (NETs) have been well documented in the ALI model of bacterial infection. In the present study, we demonstrated that poly I:C could induce pulmonary NETs. Upon poly I:C intratracheal inoculation, neutrophil infiltration in the bronchoalveolar lavage fluid (BALF) was significantly increased. Furthermore, the inflammatory cytokines IL-1β, IL-6, and TNF-α in the lung were also significantly elevated. Neutrophil depletion abolished NETs and decreased both neutrophil infiltration and IL-1β in the lung. As expected, DNase I, an inhibitor of MPO and NADPH, decreased pulmonary inflammation and NETs. Blocking of the poly I:C receptor TLR3 reduced lung inflammation and NETs. The MAPK kinase inhibitor p38 diminished the formation of NETs and restored the expression of the tight junction protein claudin-5 in the mouse lung when challenged with poly I:C. In summary, poly I:C induced the formation of pulmonary NETs and ALI, which may be associated with the activation of p38 MAPK and the decreased expression of claudin-5

Vitamin D and IL-10 Deficiency in Preterm Neonates With Bronchopulmonary Dysplasia

Introduction: Vitamin D deficiency and inflammation are involved with bronchopulmonary dysplasia (BPD) in preterm neonates; however, the clinical evidence still remains scarce. We hypothesized that vitamin D and inflammatory cytokines may be risk factors for BPD in infants.Methods: Preterm infants born between 28 and 31 weeks' gestation were recruited between January 2016 and 2017. Blood samples were all collected at corresponding time points. Vitamin D was measured using an automatic biochemical analyzer, and inflammatory cytokines (TNF-α, IL-1β, IL-6, and IL-10) were measured using ELISA.Results: The baseline characteristics for preterm infants without BPD (non-BPD control, n = 20) or with BPD (n = 19) were similar. In the blood samples collected 24-h post birth, vitamin D was significantly reduced in the BPD neonates (non-BPD vs. BPD, 28.96 ± 3.404 vs. 17.99 ± 2.233 nmol/l, p = 0.0134). Inflammatory cytokines TNF-α, IL-1β, and IL-6 were comparable in both groups. The anti-inflammatory cytokine IL-10, however, was significantly decreased in 24-h blood samples from BPD preterm infants (non-BPD vs. BPD, 44.61 ± 10.48 vs. 11.64 ± 2.351 pg/ml, p = 0.0054). In the BPD infants with mild or moderate disease, vitamin D deficiency was quite similar. IL-10 deficiency, however, was more aggravated in the BPD infants with moderate disease. No changes in Vitamin D or cytokines (TNF-α, IL-1β, IL-6, and IL-10) were observed for blood samples collected 2 or 4 weeks after birth.Conclusion: In our pilot study, Vitamin D and IL-10 levels at 24-h of life were risk factors for the development of BPD in very preterm infants

Measuring urban resilience to climate change in three chinese cities

Building an urban resilience index results in developing an increasingly popular tool for monitoring progress towards climate-proof cities. This paper develops an urban resilience index in the context of urban China, which helps planners and policy-makers

A heterozygous moth genome provides insights into herbivory and detoxification

How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemically related host plants1, but the genetic and molecular bases for adaptation to plant defense compounds remain poorly understood2. We report the first whole-genome sequence of a basal lepidopteran species, Plutella xylostella, which contains 18,071 protein-coding and 1,412 unique genes with an expansion of gene families associated with perception and the detoxification of plant defense compounds. A recent expansion of retrotransposons near detoxification-related genes and a wider system used in the metabolism of plant defense compounds are shown to also be involved in the development of insecticide resistance. This work shows the genetic and molecular bases for the evolutionary success of this worldwide herbivore and offers wider insights into insect adaptation to plant feeding, as well as opening avenues for more sustainable pest management.Minsheng You … Simon W Baxter … et al

Measuring urban low-carbon sustainability in four Chinese cities

Practices and research on measuring traditionally urban sustainability abound, therefore the challenge now is related to how the urban carbon issues are included into current measuring methods, thus there is a need to develop methods for measuring urban low-carbon sustainability. In this paper, a simple method, which is based on low-carbon sustainability index, is developed. The overall urban low-carbon sustainability index is the weighted sum of 11 single indices, and each single index is defined as the indicator assessing the development level against the baseline. The baseline is often the criteria or the minimum requirement of low-carbon sustainability. Case studies in four Chinese cities have put this method into practice, and the results show that all four selected cities fail to pass the testing of sensible low-carbon sustainability rule and they are all in weakly low-carbon sustainable development. Although the four cities have made great progress in their capacity building on pollution control and their capacities on wastewater treatment, main pollutants' removal and household and hazardous wastes treatment are enough to meet the needs of local development, they are all facing the great challenges on using of sustainable energy, offsetting of CO2 emissions and adoptions of nature-based solutions. The method developed by this research is a useful tool for decision makers identifying whether the local development is not on a low-carbon sustainable path

RESEARCH ON THE IMPACT OF FRICTION COEFFICIENT TO SCALE IN COLD ROLL-BEATING FORMING

Scale of forming surface in cold roll-beating forming process is a major defect. Controlling scaly defects is an important method to improve forming surface quality. According to the basic principle of cold roll-beating forming,the reasons and impact factors of scaly generation are analyzed. The finite element model of cold roll-beating forming was established by the finite element analysis software ABAQUS and the red copper was selected as sheet material. Under the up-beating condition and down-beating condition,the effects of friction coefficient to scaly height and scaly interval were studied. The results show that scaly height increases with the increase of friction coefficient in down-beating,while decrease in up-beating,scaly interval almost invariant in both roll-beating ways. Cold roll-beating forming experiment was carried out in refit milling machine and cross section parameters of scale in forming workpiece surface were measured by Leica DCM3D. In terms of actual measurement condition,experiment results with simulation results are uniformly. The correctness of finite element simulation is verified by experiment.Provide reference for inhibiting strip defects by selecting roll-beating methods and process parameters and improving both workpiece surface quality and dimensional precision

Influences of Vibration Parameters on Formability of 1060 Aluminum Sheet Processed by Ultrasonic Vibration-Assisted Single Point Incremental Forming

With increasing design complexities of thin-walled parts, the requirement of enhanced formability has impeded the development of the single point incremental forming (SPIF) process. In the present research, the ultrasonic vibration-assisted single point incremental forming (UV-SPIF) method was introduced to increase the formability of sheet metals. AL1060 aluminum alloy was adopted as the experimental material, and a truncated cone part was considered as the research object. The simulation model of UV-SPIF was established to analyze the distribution of plastic strains in the formed part. A forming angle was selected as the measuring index of formability of the aluminum sheet, and the influences of different vibration parameters on formability were evaluated. An experimental platform was devised to verify the accuracy of the obtained simulation results. It was found that ultrasonic vibration effectively improved the forming limit of the sheet. When the amplitude was 6 µm and the frequency was 25 kHz, the sheet yielded the best formability with the largest forming angle of 67 degrees